Wireframe Ventures backs early-stage founders focused on the health of people and the planet. Co-founders Harsh Patel and Paul Straub make initial investments of $500K to $2m at the seed or pre-seed stage, and then work closely with founders to turn their world changing ideas into scaled companies. For example, Wireframe led the seed round in Span.io, to reinvent the hundred year old electric panel, and has since raised over $120M to bring his vision from concept to commercial deployment, and frequently makes early investments in companies at the forefront of scientific innovation like Mammoth Biosciences, co-founded by Trevor Martin and Nobel Prize winner Professor Jennifer Doudna.